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Mesothelioma and Asbestos Exposure Anyone who uses products containing asbestos are at risk of ingesting asbestos fibers. These fibers penetrate the chest cavity's lining or abdomen, also referred to as the peritoneum and pleura. The exposure to asbestos increases the lifetime risk of malignant, mesothelioma that is peritoneal or pleural. Although the risk is believed to diminish after 40 years of exposure, asbestos exposure of any kind can be dangerous. Age The older a person gets when they are exposed the more likely they will develop mesothelioma. Mesothelioma affects the mesothelium – an extremely thin layer that surrounds the major organs of the body. The cancerous cells expand uncontrollably and form tumors. Mesothelioma is typically diagnosed in people who were exposed to asbestos, either in their work or as a member of someone who worked with asbestos. Exposure to asbestos can cause mesothelioma due to the irritation of the mesothelium. Pleural mesothelioma can be found in the lungs' linings, but it can also affect the linings of the abdomen and peritoneum, as well as the lining of the heart. Asbestos, a naturally occurring mineral is extremely durable and heat-resistant. Tallahassee asbestos lawsuit was widely used in the construction industry, insulation and other industrial applications prior to the 1980s. During this period many millions of Americans were exposed to asbestos due to their jobs or because they were close to an exposed loved one. When asbestos is disturbed it releases fibers into the air. These can be inhaled, and they're too tough for the body to break down or process. The fibers could be trapped in the lungs, causing irritation that may lead to cancer. Mesothelioma symptoms are typically not likely to manifest until a long time after exposure to asbestos. The symptoms are similar to those of other types of cancer but they can also be fatal if not treated. Men are more likely to be affected by mesothelioma more than women. It is also more often diagnosed for those who are older than 45. Miners, shipbuilders, railroad workers, and people who handled asbestos-containing items are at the greatest chance of developing mesothelioma due to exposure to asbestos in the workplace. Family members of these people are also at greater risk since asbestos could be found on their clothing. Smoking A person's chances of getting mesothelioma increase the longer they're exposed asbestos. This is because of the lengthy latency period, which can take between 20 to 60 years from the first exposure to the disease until it is diagnosed. Mesothelioma can be found in various parts of the body, based on the type and quantity of asbestos. Pleural mesothelioma can be found in the lining between the lung cavity and chest wall (the pleura). Peritoneal mesothelioma develops in the abdominal lining, which is known as the peritoneum. People who have been exposed to asbestos most often develop mesothelioma in their chest or lungs. People who worked in the power generation, shipbuilding and construction industries are most at risk. However, mesothelioma can also develop in individuals who were exposed to asbestos at home or at school. Children and spouses of asbestos-exposed workers can carry asbestos-containing particles from their workplace home and smear them on their clothes, skin, and hair. This puts them at risk. Mesothelioma sufferers are usually white and older than 65. They are more likely to have an occupation with a blue collar or military background. The United States Navy and other branches of the military used asbestos extensively because of its properties to resist flames, and millions of veterans may have been exposed to it. Mesothelioma can form when a person's DNA undergoes alterations which cause cells to multiply unchecked. This causes the development of tumors, which eventually develop into mesothelioma. The disease can affect the entire body however it is most common in the chest and abdomen. Smoking does not cause mesothelioma. However it increases the risk of developing this cancer by increasing the amount of asbestos people breathe in. Therefore, anyone who has been exposed to asbestos should consider quitting smoking. A person's treatment plan for mesothelioma should include a doctor who is knowledgeable about asbestos exposure and risk factors. A specialist in mesothelioma who is knowledgeable to assist them determine the best approach to treat this rare cancer. The doctor will determine whether the patient is suitable for immunotherapy or experimental treatments. Asbestos Exposure Asbestos is a naturally occurring mineral that is utilized in many different products such as flooring, roofing, and insulation. Anyone who works with asbestos-containing products make them, or manufacture them, or work with them are at a greater risk of being exposed. Exposure to asbestos fibers can lead to breathing them into the lungs, where they cause illness and cancer. Many asbestos-related illnesses are not diagnosed until it's too late due to a long latency period between exposure and the appearance of symptoms. Mesothelioma is the most deadly of asbestos diseases, is no exception. Mesothelioma symptoms can appear between 20 and 60 years after asbestos exposure. The most common way that people are exposed. All jobs that involve asbestos handling or use include those in construction, manufacturing automobile mechanics, construction, and electrical. However, people can also be exposed to asbestos through home activities, like smoking cigarettes or renovating older homes that contain asbestos. Inhalation of asbestos is the main mesothelioma causing agent. Inhaled asbestos fibers can travel to the lung, where they cause irritation to the lining known as the pleura. This irritation causes the formation of thickened patches on the pleura (pleural plaques) and fibrosis of the lungs. As the disease advances, it could cause to the accumulation of fluid within the chest cavity and eventually lung cancer. Mesothelioma can also affect the lining of other organs, such as the abdomen and the heart. People who are exposed to asbestos at work are at the greatest risk of developing mesothelioma. However, those with a family history of mesothelioma or other asbestos-related illnesses are at risk as well. A person's risk is also increased if they have been exposed to asbestos at multiple times during their lifetime. Smoking cigarettes can increase the risk of mesothelioma, but it can worsen the condition for those who are already diagnosed. If you have an history of exposure to asbestos and experience mesothelioma quitting smoking can help you live longer and improve the outcome of your treatment. Tell your doctor if you have been exposed to asbestos or experience any new symptoms such as abdominal pain or difficulty to breathing. They can prescribe medication or perform surgery to treat the disease. Genetics Many cancers are linked to genetics that means a person's genes increase the likelihood of developing a particular illness. Mesothelioma, however, does not have a gene component. The exposure to asbestos is the most important factor. Asbestos fibers can get into the body via swallowing or inhalation, and then stick to the tissues of the chest, abdomen or the heart. These fibers that are loose can cause damage to the cells that comprise these small linings over time. This can result in mesothelioma. Despite this, mesothelioma does not affect every person who is exposed. Researchers believe that other factors could affect the likelihood of developing mesothelioma after asbestos exposure. This includes the person's age and gender, their family history of mesothelioma or other illnesses, and whether they have additional risk factors such as smoking. Men are more likely than women to develop mesothelioma. This is because men were more likely than women to have been exposed to asbestos in the workplace. It can take between 20 and 60 years for mesothelioma to be diagnosed following a person's initial exposure to asbestos. A faulty gene is another risk factor for mesothelioma. In a study of two families with high mesothelioma rates scientists discovered that nearly all members of the family had an abnormal gene on their short arm chromosome 3 This gene, dubbed BAP 1 regulates the movement of calcium within cells. With a faulty gene this process is broken and calcium levels decrease. This causes asbestos to transform healthy cells into cancerous ones and trigger mesothelioma. A mutated gene can also increase the chance of developing mesothelioma due to asbestos exposure. The mutated gene causes an increase in white blood cells. These cells are responsible for fighting cancerous cells. The type of asbestos to which an individual was exposed as well as their work can increase a person's mesothelioma-related risk. The polio vaccine, given to children between 1940 and 1950, could also increase a person’s mesothelioma risk by exposing them the cancer-causing SV40.